“I said yes and hosted the event, which starred Ellen DeGeneres, Rosie O’Donnell, and others.” he said. Saget told NIH Medline Plus Magazine in 2019 that years before he “got a call from someone I did not know asking me to host a comedy fundraiser for a disease I knew very little about.” The star actually first became involved with the Scleroderma Research Foundation (SRF) prior to his sister’s diagnosis with the chronic disease, which can lead to a hardening and tightening of connective tissue and skin. But it was the death of his beloved sister Gay following a battle with the autoimmune disease scleroderma which transformed him into an avid advocate for raising money to find a cure.
